Ependymitis granularis is pseudo lesion of brain or normal phenomenon within brain, that may be seen in all age groups and shouldn't be mistaken for brain disease.
This is a focal breakdown of the ependymal lining (thin epithelial membrane lining the ventricular system of the brain) and on MRI is shown as hyperintensity signal in front of the anterior horn of ventricules.
Areas of brain damages or damaged brain cells, usually are replaced with so called supporting cells within the brain, known as glia or neuroglia, in process of glosis.
Gliosis is a scar tissue in brain.
Physical trauma, brain infection, neurodegenerative disease like Parkinson's, Alzheimer's disease, autoimmune disease like multiple sclerosis, all can trigger gliosis in brain.
Disc herniation means that the central, soft part of the disc has protruded causing pressure to certain nerves, and in cases when the herniation is bigger it may cause pressure on the spinal cord, too.
The most common symptom of a cervical disc herniation is neck pain that spreads down to the arm in various locations, and when the herniation is between C4/C5 you are most likely feeling pain, numbness, and weakness at your shoulder.
Pressure of spinal cord will lead to arm weakness, tightness of movement and altered sensation.
This should be corrected as soon as possible, since prolonged pressure on the spinal cord may result in permanent injury and disability.
Best wishes!
Marija
