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Conditions and Diseases > Bacterial Disorders Forum > Bloodborne Neisseria Infection
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Q: Bloodborne Neisseria Infection
asked by: jxricker on September 28th, 2008
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If a child with a bloodborne neisseria infection had been treated with gentamicin, and after treatment neisseria could not be found in her blood but her symptoms became worse, then why did antibiotic treatment make her symtoms increase?
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rooted
replied on September 29th, 2008
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Is it possible that another bacterial infection is also present?
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jxricker
replied on October 2nd, 2008
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Neisseria infection
The answer was in front of my face the whole time. It's because when the cell wall of the bacteria is lysed and the cell dies, it releases endotoxins.
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nurseKiki
replied on March 25th, 2009
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The answer...
Niesseria is a gram-negative infection. Because it's bean-shaped and paired capsules it creates a protection. Without a host neisseria cannot survive long outside of the host cell where they are exposed to drying, cold, acidity, or light. Because it is gram negative and lives within a host cell, when destroyed by gentamycin, it releases a harmful endotoxin A. Which can only be released by the destruction of a gram negative cell because it has the lipopolysachrides layer (Lipid A) Lipid A is an endotoxin which is toxic in the bloodsteam and GI tract. It can cause shock,vasodilation, inflammation, and blood clotting in humans. Which is the cause of her worsening symptoms. Although gram negative cells are more susceptable to antibitic therapy, when they are destroyed kills you by the release of Endotoxin A. I hope this helps everyone who has this question on the Micro test 2!! LOL
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jxricker
replied on March 28th, 2009
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Thanks for the reply. Although this wasn't initially for the test, it did show up there later. LOL.
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menthol
replied on June 15th, 2009
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what are the effects of erythromycin on 50s subunit of ribosome on a prokaryotic cell
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