Although, depression, anxiety and irritability are side effects of hysterectomy, there is no clinical evidence that hysterectomy is associated with an increase in postoperative psychiatric illness.
However, it is well known that, reproduction-related hormonal changes raise the risk of depressive episodes. That happens during and after pregnancy, after delivery, breastfeeding and during menopause (you have surgically induced menopause), and, in a group of susceptible women, the hormonal changes might trigger “normal” mood changes that can then “take on a life of their own.”

Many doctors state that patients should not expect full stabilization of bipolar episodes for at least 3-4 weeks.
Depression does not respond instantaneously to resumed medication, typically taking up to 6 weeks to respond.
Mania may disappear slowly, or it may become depression.