Well, as a girl and someone who has been in her position, the best advice I can give you is to end things now while you still can. I understand you wanting to make a life with her, but is that really the kind of life that you want to live?? Knowing that she has done this twice and always having the thought in the back of your mind that she might do it again. Reading how she went for a girls night out that turned into a party makes me think that she is probably either already cheating (more than a kiss) or she is thinking about it. I have never been on a girls night out that turned into a party without prior notice. I hate to say it, but you were lied to. I have been in her situation too and I have also told a boyfriend that I was hanging out with a girlfriend so I could see another guy.
The disease you have should not make a difference in this situation. I am a firm believer that there is someone out there for everyone, someone who loves you for who are are and not how much money you have. You just have to leave your current situation or you will never find the one that you were meant to be with. This girl very obviously isn't that person. A true "soul mate" wouldn't cause you pain, but yet give you nothing but happiness.
I really hate to say it to you, but get out! Run! You will end up getting hurt even worse in the end and a marriage cannot work if only one person is giving to make it work. Hope this helps!