trapach - this below supports your case but it is quite a low sample
ERECTILE DYSFUNCTION
Relaxation of the cavernous smooth muscle is required for penile erection, while nitric oxide triggers such relaxation. Stanislavov
R and Nikolova V. Seminological Laboratory SBALAG, Bulgaria, investigated the possibility of overcoming erectile dysfunction (ED)
by increasing the amounts of endogenous NO.
Pyconogenol is known to increase production of NO by nitric oxide syntase together with L-arginine as substrate for this
enzyme. They orally administered 40 men, aged 25-45 years, with pycnogenol and L-arginine. They found that treatment with a
combination of L-arginine and Pycnogenol for the following month increased the number of men with restored sexual ability to
80%. And, 92.5% of the men experienced a normal erection, after the third month of treatment. They concluded that oral
administration of L-arginine in combination with Pycnogenol causes a significant improvement in sexual function in men with ED.