During the 1950s and 1960s, amphetamines were often prescribed for conditions such as fatigue, obesity, and mild depression. Such use has stopped because the drugs are very addictive, and are now considered controlled substances.

Over-the-counter (OTC) amphetamine look-alike drugs are often abused. These drugs typically contain caffeine and other stimulants, and are sold as appetite suppressants or stay-awake/stay-alert aids.

I'd suggest that you look into the following reports:

http://www.emedicine.com/emerg/byname/toxi city--amphetamine.htm

Kalant, O.J. (1966) The amphetamines: Toxicity and addiction Springfield, Ill: Charles C Thomas Publishers.

Ellinwood, E.H, (1967) Amphetamine Psychosis. I. Description of the individuals and processes. Journal of Nervous and Mental Disease, 144, 273-283.

I suffered an Amphetamine Psychosis in 2004 after my first doses of ADHD drugs. In fact it lead to a seizure.