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Q: Alternatives to Ultram ER
asked by: KBman on October 15th, 2008
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I was wondering if anyone had any experience switching from Ultram (Tramadol) and/or Hydrcodone for pain/depressive symptoms. I have been on Ultram for approximately 9 years now, switching to Ultram ER for the past year (affect lasts longer).

I am 40. I first took Ultram for non-specific head pain (that seemed to get bad as soon as I awoke from sleeping). It gave me energy, took away my head pain, and lifted my mood - big time (for over 7 years). The Ultram ER didn't seem to be working as well for the past 6 months, so I began to combine this with Hydro, with good results - until about 2 weeks ago. I seem to be in some sort of funk. Went to doctor 1 week ago with non-specific dizziness/disorientation and very fatigued. Blood tests come back normal. He claims I have classic symptoms of depression. (I'm thinking, if this IS depression, I have never, ever been depressed in my life before; because my head, mood, thinking is horrible, my joints/muscles ache, I have extreme lethargy, and I'm not sleeping the way I should be.) Question

Anyway, has anyone had success switching to another pain medication similar to the way Ultram works? Tried numerous anti-depressant medications over the years, but every single one was way, way, way too strong for my body to handle, even at the lowest possible dose.
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Dr. Bruce Harrow , MD
replied on July 9th, 2009
Neither tramadol nor hydrocodone are anti-depressants. Poorly controlled pain causes depression in most people eventually and controlling the pain often ends the depression. Both drugs are opiates, tramadol weak and hydrocodone moderately strong. Combining the 2, kind of like paying a $100 bill with four 20s and twenty 1s but it's hard to argue with success, is ok but can increase the risk of opiate side effects. Your symptoms might be a side effect of the drugs themselves and if so, usually stops with stopping one or both or switching to a different opiate.




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