I am asking this for my sister who is at work and unable to access the internet. I'm going to try to cram as much background information in here as possible. She is 27 years old. She is currently taken Worfrin for a blood clot that she has in her arm. About a week ago she started having abdominal cramping as if she needed to have a bowel movement. When she goes it is either only mucus that comes out or nothing at all. She is straining so much that I am sure hemorrhoids have formed because she says her anus burns a lot. She used to be able to go home on her lunch hour to take care of business (if you know what I mean) but now she isn't able to do that. Could the change in her schedule be the reason for her constipation. She has also lost a lot of weight (over 20 pounds in five months)with no change in diet and exercise. She had blood tests and stool tests run yesterday and everything came back normal. What could be causing this irregularity?