A new pilot study explored the possible effectiveness of magnesium supplementation for hot flash reduction in breast cancer patients. For this small pilot study, investigators recruited 25 breast cancer patients who were experiencing at least 14 hot flashes per week and asked them to take 400 milligrams of magnesium oxide every day for 4 weeks. The breast cancer patients were allowed to increase their magnesium supplementation to 800 mg per day if they felt it was necessary. The results of the study showed:
- 17 of the 25 breast cancer patients increased their magnesium dose to 800 mg per day.
- Hot flashes were reduced by about 41% from about 52 hot flashes per week on average to an average of 28 hot flashes per week.
- Hot flash score was reduced by 50% from a score of about 110 to a score of about 48.
- 14 of the breast cancer patients experienced a reduction in hot flash score of more than 50%.
- 76% of the breast cancer patients (19 of 25) showed as least a 25% decrease in hot flash score.
- Other menopause symptoms including fatigue, sweating, and distress were also reduced by magnesium supplementation.
- Reported side effects were considered minor and included one case of headaches, one case of nausea, and 2 cases of diarrhea.
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